Paste your protein or nucleotide FASTA sequence(s) into the text area below. (Sample FASTA sequence: 2009 H1N1 NA, known Tamiflu-resistant case)         OR upload your protein or nucleotide sequences in a FASTA file         The server can automatically determine the type of input (protein or nucleotide) and the closest reference sequence to compare. Also mixtures of genes/proteins (e.g. HA and NA or all genes of the same patient) can be provided as input. To be much faster (automatic mode needs to check many possibilities) or to compare with more remotely related sequences/strains, it is possible to select a specific reference sequence by choosing below.       Compare with: Automatic detection of closest reference sequence ----------------------------------- 2009 H1N1 Mexican-type (please select from below) ----------------------------------- NA 2009 H1N1 Texas/04 Segment 6, Neuraminidase (with mutation warning and structure visualization) HA 2009 H1N1 Texas/04 Segment 4, Hemagglutinin (with mutation warning and structure visualization) PB2 2009 H1N1 Texas/04 Segment 1, polymerase B2 (with preliminary mutation warning) PB1 2009 H1N1 Texas/04 Segment 2, polymerase B1 (with preliminary mutation warning) PA 2009 H1N1 Texas/04 Segment 3, polymerase A (with preliminary mutation warning) NP 2009 H1N1 Texas/04 Segment 5, nucleocapsid protein M2 2009 H1N1 Texas/04 Segment 7, matrix protein 2 M1 2009 H1N1 Texas/04 Segment 7, matrix protein 1 NS2 2009 H1N1 Texas/04 Segment 8, nuclear export protein NS1 2009 H1N1 Texas/04 Segment 8, nonstructural protein 1 ----------------------------------- 2009 H1N1 New York-type (please select from below) ----------------------------------- NA 2009 H1N1 NewYork/20 Segment 6, Neuraminidase (with mutation warning and structure visualization) HA 2009 H1N1 NewYork/20 Segment 4, Hemagglutinin (with mutation warning and structure visualization) PB2 2009 H1N1 NewYork/20 Segment 1, polymerase B2 (with preliminary mutation warning) PB1 2009 H1N1 NewYork/20 Segment 2, polymerase B1 (with preliminary mutation warning) PA 2009 H1N1 NewYork/20 Segment 3, polymerase A (with preliminary mutation warning) NP 2009 H1N1 NewYork/20 Segment 5, nucleocapsid protein M2 2009 H1N1 NewYork/20 Segment 7, matrix protein 2 M1 2009 H1N1 NewYork/20 Segment 7, matrix protein 1 NS2 2009 H1N1 NewYork/20 Segment 8, nuclear export protein NS1 2009 H1N1 NewYork/20 Segment 8, nonstructural protein 1 -------------------------------- 2007 H3N2 Circulating seasonal (please select from below) -------------------------------- HA 2007 H3N2 Brisbane/10 Hemagglutinin (with mutation warning and structure visualization)       Additional settings:   ignore low quality bases for nucleotide input (indicated by lower case, except for all lower case sequences)   for 2009 H1N1 and automatic mode: take patient New York 20 (New York-type) rather than Texas 4 (Mexican-type) as default reference        (estimated time needed: ~10 seconds per sequence in automatic mode)